Author: Mushroom References

The effects of freeze-dried Ganoderma lucidum mycelia on a recurrent oral ulceration rat model

Conventional scientific studies had supported the use of polysaccharides and β-glucans from a number of fungi, including Ganoderma lucidum for the treatment of recurrent oral ulceration (ROU). Our aim of the present study was to evaluate whether freeze-dried powder from G. lucidum mycelia (FDPGLM) prevents ROU in rats. Xie, L., Zhong, X., Liu, D., Liu, …

Read More The effects of freeze-dried Ganoderma lucidum mycelia on a recurrent oral ulceration rat model

Two novel diterpenoids, erinacines H and I from the mycelia of Hericium erinaceum

Novel diterpenoids, erinacines H (1) and I (3), were isolated from the cultured mycelia of Hericium erinaceum. The structures of the compounds were determined by interpretation of the spectral data. Erinacine H showed stimulating activity of nerve growth factor (NGF)-synthesis. Lee, E. W., Shizuki, K., Hosokawa, S., Suzuki, M., Suganuma, H., Inakuma, T., . . …

Read More Two novel diterpenoids, erinacines H and I from the mycelia of Hericium erinaceum

Pyrrole alkaloids and ergosterols from Grifola frondosa exert anti-α-glucosidase and anti-proliferative activities

Previously, polysaccharides with hypoglycemic effects from G. frondosa were reported by us. To explore compounds against α-glucosidase and human tumor cells, three extractive fractions (GF-1–GF-3) were prepared from G. frondosa ethanol extraction (GF) by chromatographic column. Rather than GF-1 and GF-2, the fraction GF-3 demonstrated inhibitory actions against α-glucosidase and proliferation of human tumor cells …

Read More Pyrrole alkaloids and ergosterols from Grifola frondosa exert anti-α-glucosidase and anti-proliferative activities

Lanostane triterpenes from the mushroom Ganoderma resinaceum and their inhibitory activities against α-glucosidase

Eighteen previously undescribed lanostane triterpenes and thirty known analogues were obtained from the fruiting bodies of Ganoderma resinaceum. Resinacein C was isolated from a natural source for the first time. The structures of all the above compounds were elucidated by extensive spectroscopic analysis and comparisons of their spectroscopic data with those reported in the literature. …

Read More Lanostane triterpenes from the mushroom Ganoderma resinaceum and their inhibitory activities against α-glucosidase

Ganoderma applanatum secondary metabolites induced apoptosis through different pathways: In vivo and in vitro anticancer studies

Ganoderma applanatum is a widely distributed saprobic or parasitic mushroom, it was found at the bases of decaying logs in Hakozaki Higashi-ku Fukuoka-shi. Japan. The mushroom was extracted with 80% methanol, and LC-HRMS analysis was conducted to illustrate the bioactive ingredients. The cytotoxicity of the total metabolite extract was evaluated against human colon cancer cell …

Read More Ganoderma applanatum secondary metabolites induced apoptosis through different pathways: In vivo and in vitro anticancer studies

Screening of antifungal activity of Ganoderma Lucidum extract against medically important fungi

Antimicrobials of plant origin are effective in the treatment of infectious disease while simultaneously mitigating many side effects that are often associated with synthetic antimicrobials. In the present study crude aqueous and ethanolic extract of Ganoderma lucidum was evaluated for its antifungal activity against the clinically important fungi namely Candida albicans, Aspergillus niger, Penicillium marneffei, …

Read More Screening of antifungal activity of Ganoderma Lucidum extract against medically important fungi

The effects of freeze-dried Ganoderma lucidum mycelia on a recurrent oral ulceration rat model.

Conventional scientific studies had supported the use of polysaccharides and β-glucans from a number of fungi, including Ganoderma lucidum for the treatment of recurrent oral ulceration (ROU). Our aim of the present study was to evaluate whether freeze-dried powder from G. lucidum mycelia (FDPGLM) prevents ROU in rats. Xie, L., Zhong, X., Liu, D., Liu, …

Read More The effects of freeze-dried Ganoderma lucidum mycelia on a recurrent oral ulceration rat model.

Antioxidant activity of liquid cultured Inonotus obliquus polyphenols using tween-20 as a stimulatory agent

Polyphenols are major functional components of the medicinal mushroom Inonotus obliquus . Compared with the wide application of surfactants in medicinal mushroom polysaccharide production, using surfactants to enhance mushroom polyphenol production and antioxidant activity is a relatively new approach. For the first time, in the present study, we evaluated the effect of Tween-20 on the …

Read More Antioxidant activity of liquid cultured Inonotus obliquus polyphenols using tween-20 as a stimulatory agent

GC-MS Profiling of Volatile Components in Different Fermentation Products of Cordyceps Sinensis Mycelia

The fermentation products of Cordyceps sinensis (C. sinensis) mycelia are sustainable substitutes for natural C. sinensis. However, the volatile compositions of the commercial products are still unclear. In this paper, we have developed a simultaneous distillation-extraction (SDE) and gas chromatography-mass spectrometry (GC-MS) method for the profiling of volatile components in five fermentation products. A total …

Read More GC-MS Profiling of Volatile Components in Different Fermentation Products of Cordyceps Sinensis Mycelia

Effects of cordycepin on spontaneous alternation behavior and adenosine receptors expression in hippocampus.

Cordycepin, an adenosine analogue, has been reported to improve cognitive function. Important roles on learning and memory of adenosine and its receptors, such as adenosine A1 and A2A receptors (A1R and A2AR), also have been shown. Therefore, we assume that the improvement of learning and memory induced by cordycepin is likely related to hippocampal adenosine …

Read More Effects of cordycepin on spontaneous alternation behavior and adenosine receptors expression in hippocampus.

Inonotus obliquus extract induces apoptosis in the human colorectal carcinoma’s HCT-116 cell line

Because of irregular dietary habits and lifestyle in Taiwan, the incidence and mortality rate of colorectal cancer have been increasing rapidly these years. This study investigated the inhibitory activity against the proliferation of human colorectal cancer HCT-116 cells by Inonotus obliquus extracts obtained from submerged fermentation. Cell viability was measured by the reduction of MTT …

Read More Inonotus obliquus extract induces apoptosis in the human colorectal carcinoma’s HCT-116 cell line

Culture broth of Ganoderma lucidum exhibited antioxidant, antibacterial and α-amylase inhibitory activities

Culture broth of Ganoderma lucidum was determined for antioxidant, antibacterial and α-amylase inhibitory activities. The culture broth contained protein as determined by Bradford method equaled to 0.2 mg/ml and total phenol content as 0.078 mg GAE/mg protein (0.557 mg GAE/g extract). It exhibited radicals scavenging activities against ABTS+· and DPPH·radicals with a half maximal inhibitory concentration (IC50) less than 1.70 ± 0.02 and 2.28 ± 0.02 µg protein/ml, respectively …

Read More Culture broth of Ganoderma lucidum exhibited antioxidant, antibacterial and α-amylase inhibitory activities

Antimicrobial activity of ethanolic extracts made of mushroom mycelia developed in submerged culture

The ethanolic extracts of dried biomass made of mushroom mycelium produced in the submerged cultures of eight edible/medicinal macromycete species Ganoderma applanatum, Ganoderma lucidum, Laetiporus sulphureus, Flammulina velutipes, Trametes versicolor, Hericium coralloides, Pleurotus eryngii 2600 and Agaricus campestris were evaluated for their antimicrobial activities. Pathogenic tested microorganisms were represented by five bacteria and two yeasts …

Read More Antimicrobial activity of ethanolic extracts made of mushroom mycelia developed in submerged culture