Research on the availability of lovastatin in different mushroom species, mechanism of control of diseases like hypercholesterolemia and their drug efficacy are limited. Therefore, the present investigation is focused on quantitative and qualitative analysis of lovastatin from different highly preferred edible oyster mushrooms species by the consumers. The study was carried out for the determination of lovastatin content from different species of mushroom like, Pleurotus ostreatus (grey), Hypsizygus ulmarius (white) and Agaricus djamor (pink) under different culture conditions like Solid State Fermentation (SSF), Submerged Fermentation (SMF) and in the powder of dried mushroom of P. ostreatus as well. The lovastatin content was determined by UV spectrophotometric analysis and further separation, detection, quality and quantitative analysis were made in the partially purified lovastatin using High Pressure Liquid Chromatography. The lovastatin content was found to be highest in the P. ostreatus under all the given culture conditions.
Ramakrishnan, M., Dubey, C., Tulasi, V., Kislai, P., & Manohar, N. (2017). Investigation of Lovastatin, the Anti-hypercholesterolemia Drug Molecule from Three Oyster Mushroom Species. International Journal of Biomedical and Clinical Sciences, 2(4), 26-31.